The 66th Annual General Assembly and Scientific Meeting of the Japan College of Rheumatology

English Session

Symposium (Held onsite, Live and On-demand streaming)

S4

Advances on osteoarthritis pathogenesis and treatment

Monday, April 25   9:30-12:00   4F Room 10 (G401+G402)

Chairs:

Hiroshi Takayanagi

Department of Immunology Graduate School of Medicine and Faculty of Medicine The University of Tokyo, Japan

Taku Saito

Orthopaedic Surgery, Graduate School of Medicine, The University of Tokyo, Japan

S4-1
Epidemiology and treatment of osteoarthritis

David J. Hunter

Kolling Institute, University of Sydney, Sydney, Australia

S4-2
Mechanisms of synovial joint development, maintenance, and degeneration

Taku Saito

Orthopaedic Surgery, Graduate School of Medicine, The University of Tokyo, Japan

S4-3
Application of iPS cell-derived cartilage to regenerate articular cartilage damage

Noriyuki Tsumaki

Department of Biochemistry and Molecular Biology, Graduate School of Medicine, Osaka University, Japan

S4-4
Join pain in osteoarthritis

Xu Cao

Johns Hopkins University, USA

S4-5
Efficacy of anti-NGF antibody in osteoarthritis

Marc Hochberg

University of Maryland School of Medicine, Baltimore, USA

S5

Rapidly changing paradigm of vasculitis treatment

Monday, April 25   14:50-16:50   1F Room 1 (G1+G2)

Chairs:

Masayoshi Harigai

Division of Rheumatology, Department of Internal Medicine, Tokyo Women’s Medical University School of Medicine, Japan

Tomonori Ishii

Clinical Reserch, Education and Innovation Center, Tohoku University Hospital, Japan

S5-1
SARS-CoV-2-associated vasculopathy and vasculitis - an enigmatic disease

Akihiro Ishizu

Department of Medical Laboratory Science, Faculty of Health Sciences, Hokkaido University, Sapporo, Japan

S5-2
Useful biomarkers in the management of vasculitides

Jun Ishizaki

Department of Hematology, Clinical Immunology and Infectious Diseases, Ehime University Graduate School of Medicine, Japan

S5-3
Emerging molecular targeted therapy of microscopic polyangiitis and granulomatosis with polyangiitis - when, which and how to use?

Masayoshi Harigai

Division of Rheumatology, Department of Internal Medicine, Tokyo Women's Medical University School of Medicine, Japan

S5-4
Optimizing treatment of large vessel vasculitides-the time is now

Takahiko Sugihara

Division of Rheumatology and Allergy, Department of Internal Medicine, St. Marianna University School of Medicine, Japan

S6

Recent advances in macrophage and osteoclast research in rheumatoid arthritis

Monday, April 25   14:50-16:50   3F room 4(G301+G302)

Chairs:

Hiroshi Takayanagi

Department of Immunology Graduate School of Medicine and Faculty of Medicine The University of Tokyo, Japan

Takeshi Miyamoto

Department of Orthopedic Surgery, Kumamoto University, Japan

S6-2
Resident synovial macrophages as gate-keepers of joint inflammation

Gerhard Krönke

University of Erlangen, Germany

S6-4
Synovial tissue macrophages in joint homeostasis, Rheumatoid Arthritis, and disease remission

Mariola Kurowska-Stolarska

Research into Inflammatory Arthritis Centre Versus Arthritis (RACE), University of Glasgow, UK

S7

Multi-layer omics research of human immunology

Monday, April 25   14:50-16:50   4F room 10 (G401+G402)

Chairs:

Yukinori Okada

Department of Statistical Genetics, Osaka University Graduate School of Medicine, Japan / Laboratory for Systems Genetics, RIKEN Center for Integrative Medical Sciences, Japan

Hisashi Arase

Laboratory of Immunochemistry, WPI Immunology Frontier Research Center, Osaka University, Japan

S7-1
Interpreting immune disease GWAS signals with single cell transcriptomics from immune cells

Gosia Trynka

Wellcome Sanger Institute, UK

S7-2
Cross-tissue, single-cell stromal atlas identifies shared pathological fibroblast phenotypes in four chronic inflammatory diseases

Ilya Korsunsky

Division of Rheumatology, Inflammation and Immunity, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA / Center for Data Sciences, Brigham and Women's Hospital, Boston, MA, USA / Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA / Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA / Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA

S7-3
Novel function of MHC molecules in the pathogenesis of autoimmune diseases

Hisashi Arase

Laboratory of Immunochemistry, Immunology Frontier Research Center, Osaka University, Japan / Department of Immunochemistry, Research Institute for Microbial Diseases, Japan

S7-4
Genetics of rheumatoid-associated interstitial lung disease

Philippe Dieude

Université de Paris, INSERM UMR 1152, Paris, France / Service de Rhumatologie, Hôpital Bichat-Claude Bernard, AP-HP, F-75018, Paris, France

S7-5
Microbiome analysis of autoimmune diseases

Yukinori Okada

Department of Statistical Genetics, Osaka University Graduate School of Medicine, Japan / Laboratory for Systems Genetics, RIKEN Center for Integrative Medical Sciences, Japan

S17

A multifaceted approach to the treatment of autoimmune diseases

Wednesday, April 27   8:30-11:00   4F Room 10 (G401+G402)

Chairs:

Kunihiro Yamaoka

Department of Rheumatology and Infectious Diseases, Kitasato University School of Medicine, Japan

Jon T. Giles

Columbia University, College of Physicians & Surgeons, USA

S17-1
Advanced understanding of the pathophysiology of Spondyloarthropathy

Georg A. Schett

FAU Erlangen Nürnberg, Germany

S17-2
What should we aim for in treatment of SLE?

Eric Morand

Monash University, Melbourne, Australia

S17-3
Managing Rheumatoid Arthritis: Now and the Future

Jon T. Giles

Columbia University, College of Physicians & Surgeons, USA

S17-4
COVID-19 in autoimmune inflammatory rheumatic diseases

Jeffrey A. Sparks

Brigham and Women's Hospital, Harvard Medical School, USA

S17-5
Treatment of interstitial lung disease in autoimmune diseases

Masataka Kuwana

Department of Allergy and Rheumatology, Nippon Medical School, Japan

S18

Precision medicine in rheumatic diseases

Wednesday, April 27   14:40-17:10   1F Room 1 (G1+G2)

Chairs:

Tsutomu Takeuchi

Saitama Medical University, Japan / Keio University, Japan

Yoshiya Tanaka

The First Department of Internal Medicine, School of Medicine, University of Occupational and Environmental Health, Japan

S18-1
Genomics-driven approaches for personalized medicine

Yukinori Okada

Department of Statistical Genetics, Osaka University Graduate School of Medicine, Japan / Laboratory for Systems Genetics, RIKEN Center for Integrative Medical Sciences, Japan

S18-2
Pathobiological Approaches to Precision Medicine

John D. Isaacs

Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK

S18-3
Precision medicine using immunophenotypic analysis

Shingo Nakayamada

First Department of Internal Medicine, University of Occupational and Environmental Health, Japan, Kitakyushu, Japan

S18-4
Precision medicine by multiomics analysis

Katsuya Suzuki

Division of Rheumatology, Department of Internal Medicine, School of Medicine, Keio University, Japan

S18-5
Future perspectives on precision medicine in rheumatic diseases

Daniel Aletaha

Division of Rheumatology, Medical University Vienna, Austria

Special Symposium (Held onsite, Live and On-demand streaming)

SS2 (ACR Session)

Translational Research Programs to Define Mechanisms of Complex Inflammatory Diseases

Tuesday, April 26   8:30-10:30   4F Room 10(G401+G402)

Chairs:

Yoshiya Tanaka

The First Department of Internal Medicine, University of Occupational and Environmental Health, Japan

Kazuhiko Yamamoto

Laboratory for Autoimmune Diseases, RIKEN Center for Integrative Medical Sciences, Japan

SS2-1
When normal isn't normal: understanding the skin in systemic lupus

J. Michelle Kahlenberg

Department of Internal Medicine, Rheumatology, University of Michigan, Ann Arbor, Michigan, USA

SS2-2
Somatic Mutations in Rheumatologic Diseases: VEXAS Syndrome and Beyond

Peter Grayson

National Institutes of Health, USA

SS3 (EULAR Session)

Innovations in Arthritis - New frontiers of Rheumatology?

Tuesday, April 26   14:10-16:10   4F Room 10(G401+G402)

Chairs:

Tsutomu Takeuchi

Saitama Medical University, Japan / Keio University, Japan

Atsushi Kawakami

Nagasaki University Graduate School of Biomedical Sciences, Japan

SS3-1
Innovative Imaging in RA

Annamaria Iagnocco

Università degli Studi di Torino, Turin Italy

SS3-2
Innovative Imaging in PsA

Xenofon Baraliakos

Rheumazentrum Ruhrgebiet Herne / Ruhr-University Bochum, Germany

SS3-3
Precision medicine in RA

Daniel Aletaha

Division of Rheumatology, Medical University Vienna, Austria

SS3-4
Precision Medicine in Psoriatic Arthritis

Iain B. Mcinnes

University of Glasgow, UK

Educational Lecture (Held onsite and On-demand streaming)

EL7

Transforming clinical trials in rheumatology: towards patient-centric precision medicine

Monday, April 25   14:40-15:40   3F Room 5 (G303)

Chair:

Mineto Ota

Department of Functional Genomics and Immunological Diseases, Graduate School of Medicine, The University of Tokyo, Japan

Lecturer:

Costantino Pitzalis

Queen Mary University of London, UK

EL13

Why remission is not enough?

Tuesday, April 26   14:10-15:10   1F Room 2 (G7)

Chair:

Yukinori Okada

Department of Statistical Genetics, Osaka University Graduate School of Medicine, Japan

Lecturer:

Georg A. Schett

FAU Erlangen Nürnberg, Germany

EL18

Functional MRI in rheumatoid arthritis: an ideal translational tool for basic research and prediction of therapeutic outcome in the clinics

Wednesday, April 27   8:30-9:30   1F Room 2 (G7)

Chair:

Kei Ikeda

Chiba University Hospital, Japan

Lecturer:

Andreas Hess

I. f. Experimental Pharmacology, FAU Erlangen-Nürnberg, Germany

EL24

Wnt signaling in bone homeostasis and disease: Sclerostin Biology and Inhibition

Wednesday, April 27   13:50-14:50   3F Room 5 (G303)

Chair:

Yuho Kadono

Orthopaedic Surgery, Saitama Medical University, Japan

Lecturer:

Roland Baron

Department of Medicine, Harvard Medical School, Boston, USA / Department of Oral Medicine, Harvard School of Dental Medicine, USA

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